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Pfizer and BioNTech have begun a clinical trial for their Omicron-specific Covid-19 vaccine candidate, they announced in a news release on Tuesday.
The study will evaluate the vaccine for safety, tolerability and the level of immune response, as both a primary series and a booster dose, in up to 1,420 healthy adults ages 18 to 55.
The study is broken up into three groups:
Participants in the first cohort have received two doses of the current Pfizer Covid-19 vaccine at least 90 to 180 days before the study. They will receive one or two doses of the Omicron-specific vaccine.
Participants in the second cohort have received three doses of the current Pfizer Covid-19 vaccine at least 90 to 180 days prior to the study. They will receive one dose of the current Pfizer Covid-19 vaccine or the Omicron-specific vaccine.
Participants in the third cohort have not received any Covid-19 vaccine. They will receive three doses of the Omicron-specific vaccine.
The Omicron-specific vaccine will be administered as a 30-microgram dose, the same as the current vaccine.
“While current research and real-world data show that boosters continue to provide a high level of protection against severe disease and hospitalization with Omicron, we recognize the need to be prepared in the event this protection wanes over time and to potentially help address Omicron and new variants in the future,” Pfizer Senior Vice President and Head of Vaccine Research and Development Kathrin Jansen said in the release.CNN
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Pfizer CEO Albert Bourla said last month that if a new vaccine is needed for the Omicron coronavirus variant, the company will have one in March. However, a Pfizer spokesperson confirmed that the company has already begun to manufacture this vaccine.
“In the wake of Omicron, we are proactively investigating and manufacturing at risk an Omicron-based vaccine should it be needed, but we of course need to have results and discussions with health authorities as well as approvals before it would be deployed,” the spokesperson told CNN.
Expected vaccine production will not be affected if the companies need to pivot to the new vaccine, they said. CNN
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Quality: 100% soft-style combed cotton.
Color: White, Black, Red, Navy, Sport Grey, Dark Heather, Kelly Green, Royal Blue, Purple, Gold, and Brown.
Size: S, M, L, XL, 2XL, 3XL, 4XL, 5XL, 6XL.